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yifyNeurodevelopmental effects of antidepressant treatment in offspring of depressed mothers.
Developmental effects of neuropsychiatric disorders may be modified by early stress, including exposure to maternal depression. Several brain-derived neurotrophic factors (BDNF) involved in neuronal and synaptic plasticity were found to be altered in adults and children with depression and/or post-traumatic stress disorder. We aimed to assess whether maternal depression during pregnancy could impact BDNF in adult offspring and whether some antidepressant treatments may modify this neurotrophic effect. In a prospective, controlled study, we included 71 adult subjects exposed to antidepressant drugs for depression (n = 29) or to mood stabilizing treatment for bipolar disorder (n = 42), as compared to healthy controls (n = 27). BDNF concentrations in serum were measured by enzyme-linked immunosorbent assay (ELISA). A significant reduction in serum BDNF levels was found in patients treated with mood stabilizing drugs as compared to healthy controls (P = 0.05). In addition, a significant interaction was found between paternal depression and antidepressant exposure in the mean change of BDNF levels (P = 0.04). Antidepressant treatment in patients with a history of paternal depression decreased BDNF. These results suggest that alterations in BDNF could play a role in the neuroplastic changes associated with major depression, particularly in subjects with a history of paternal depression.Q:

How to use scanf(“%d”,&A) for an array of elements in C

How can I use scanf(“%d”,&A) to read an array of elements?
Like for an array like int A[5];
int main()
{
int A[5] = {1,2,3,4,5};
int i;
int *p;

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